Natural routes for post-natal transmission of murine lymphocytic choriomeningitis
نویسندگان
چکیده
منابع مشابه
Phenotypic analysis of the inflammatory exudate in murine lymphocytic choriomeningitis
The massive inflammation of the cerebrospinal fluid (CSF) which occurs in adult mice injected with lymphocytic choriomeningitis virus (LCMV) has been analyzed by flow microfluorometry (FMF). The great majority of the T cells detected by direct examination of freshly obtained CSF were found to be Lyt-2+, with an almost total absence of L3T4+ lymphocytes. The Lyt-2/L3T4 ratio of lymphocytes in bl...
متن کاملLymphocytic Choriomeningitis
Lymphocytic choriomeningitis virus (LCMV) is a pathogen, normally carried in rodents, which can cause aseptic meningitis and other conditions in humans. Most people experience a relatively mild illness and fatal infections are rare; however, pregnant women may give birth to congenitally infected infants with severe defects of the brain and eye. In a few instances, this virus has been transmitte...
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A case of lymphocytic choriomeningitis virus (LCMV) infection led to investigation of the reservoir. LCMV was detected in mice trapped at the patient's home, and 12 isolates were recovered. Genetic analysis showed that human and mouse LCMVs were identical and that this LCMV strain was highly divergent from previously characterized LCMV.
متن کاملLymphocytic Choriomeningitis Virus
There has been an upsurge of interest in lymphocytic choriomeningitis virus (LCMV) as a human pathogen and specifically as an underdiagnosed congenital infection (1,2). LCMV is a member of the Arenaviridae family of viruses. Arenaviruses have a complex life cycle involving chronic infection and shedding of the virus in rodents and episodic infections in humans (3,4). Six of the arenaviruses (La...
متن کاملLymphocytic Choriomeningitis in Michigan
We summarize the first reported case of acquired lymphocytic choriomeningitis virus (LCMV) infection in Michigan to be investigated by public health authorities and provide evidence of the focal nature of LCMV infection in domestic rodents. Results of serologic and virologic testing in rodents contrasted, and negative serologic test results should be confirmed by tissue testing.
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ژورنال
عنوان ژورنال: Laboratory Animals
سال: 1973
ISSN: 0023-6772,1758-1117
DOI: 10.1258/002367773781008597